000 03216nam a2200361 i 4500
999 _c8989
_d8989
001 ASIN9814411043
005 20210816161717.0
008 150204s2013 si a eng d
020 _a9814411043 (hardcover)
_c$149.95
020 _a9789814411042 (hardcover)
040 _cEG-NcFUE
_erda
_aEG-NcFUE
_beng
082 0 4 _223
_a615.6
_bN
245 1 0 _aNanotechnology for the delivery of therapeutic nucleic acids /
_cedited by Dan Peer.
264 1 _aSingapore :
_bPan Stanford Publishing,
_c2013.
264 2 _aLondon :
_bTaylor & Francis,
_c2013.
300 _axiii, 226 pages ;
_c23 cm
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
490 1 _aPan stanford series on biomedical nanotechnology;
_vv. 4.
500 _apharmacy bookfair2015
505 0 _a Lipoplexes and polyplexes : from gene delivery to gene expression / Gerardo Byk, Mirit Cohen-Ohana, and Fiana Mirkin -- 2. Cationic polymers for the delivery of therapeutic nucleotides / Wahid Khan, Saravanan Muthupandian, and Abraham J. Domb -- 3. Membrane/core nanoparticles for delivery of therapeutic nucleic acid / Younjee Chung and Leaf Huang -- 4. Delivery of single siRNA molecules / Caroline Palm-Apergi and Steven F. Dowdy -- 5. Cell-specific aptamer-functionalized RNAi : a new prospect for targeted siRNA delivery / Jiehua Zhou and John J. Rossi -- 6. Bioresponsive nanoparticles for the intracellular delivery of RNAi therapeutics / Kenneth Alan Howard -- 7. Lipid-like delivery materials for efficient siRNA delivery / James Dahlman, Robert Langer, and Michael Goldberg -- 8. Manipulation of leukocytes using therapeutic RNAi delivered by targeted and stabilized nanoparticles / Dan Peer -- 9. Lowering the siRNA delivery barrier : alginate scaffolds and immune stimulation / Jana McCaskill, Sherry Wu, Norliana Khairuddin, and Nigel A.J. McMillan.
520 _aNucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack of efficient and safe delivery strategies. Nanotechnology for the Delivery of Therapeutic Nucleic Acids , written by world experts in the field of nanotechnology for NA delivery, the contributing authors bring together the state of the art in delivery strategies with strong emphasis on aspects that are of essence to the pharmaceutical industry, such as stability, general toxicity, immune-toxicity, pharmacokinetics, efficacy, and validation of new drug targets using unique approaches based on exquisite nanotechnology strategies.
650 0 _aDrug delivery systems.
650 0 _aNucleic acids.
650 0 _aNanotechnology.
700 1 _aPeer, Dan,
_d1972-,
_eeditor.
830 0 _aPan stanford series on biomedical nanotechnology.
856 4 0 _3Amazon.com
_uhttp://www.amazon.com/exec/obidos/ASIN/9814411043/chopaconline-20
856 4 0 _3Abstract
_uhttp://repository.fue.edu.eg/xmlui/handle/123456789/1742
942 _2ddc
_cBK