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999 _c9246
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005 20201025092530.0
008 070823s2008 njua b 001 0 eng d
010 _a 2007935895
020 _a9781588294579 (hb)
020 _a9781597453394
035 _a(OCoLC)ocn144217208
040 _aBTCTA
_cBTCTA
_dBAKER
_dYDXCP
_dHNI
_dCOU
_dDLC
_erda
042 _alccopycat
050 0 0 _aRC268.5
_b.A6526 2008
082 0 4 _222
_a616.99407
_bA
245 0 0 _aApoptosis and cancer :
_bmethods and protocols /
_cedited by Gil Mor and Ayesha B. Alvero.
264 1 _aTotowa, N.J. :
_bHumana Press,
_c[2008]
264 4 _c©2008
300 _axi, 266 pages :
_billustartions ;
_c24 cm
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
490 1 _aMethods in molecular biology ;
_v414
504 _aIncludes bibliographical references and index.
505 0 _tModulation of apoptosis to reverse chemoresistance / Gil Mor, Michele K. Montagna, and Ayesha B. Alvero -- Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis / Suparna Mazumder, Dragos Plesca, and Alexandru Almasan -- Flow cytometry enumeration of apoptotic cancer cells by apoptotic rate / David Diaz ... [et al.] -- Detection of cancer-related proteins in fresh-frozen ovarian cancer samples using laser capture microdissection / Dan-Arin Silasi ... [et al.] -- Flow cytometric detection of activated caspase-3 / Richard Fox and Martine Aubert -- The chemofx® assay : an ex vivo chemosensitivity and resistance assay for predicting patient response to cancer chemotherapy / Stacey L. Brower, Jeffrey E. Fensterer, and Jason E. Bush -- Correlation of caspase activity and in vitro chemo-response in epithelial ovarian cancer cell lines / Ayesha B. Alvero, Michele K. Montagna, and Gil Mor -- Assessing expression of apoptotic markers using large cohort tissue microarrays / Elah Pick, Mary M. McCarthy, and Harriet M. Kluger -- Mitochondria potential, bax "activation," and programmed cell death / C. Michael Knudson and Nicholas M. Brown -- In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases / Brian W. Lee ... [et al.] -- Caspase activity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss -- Multiplex caspase activity and cytotoxicity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss -- Homogeneous, bioluminescent proteasome assays / Martha A. O'Brien ... [et al.] -- A simple method for profiling mirna expression / Jia-Wang Wang and Jin Q. Cheng -- Apoptotic caspase activation and activity / Jean-Bernard Denault and Guy S. Salvesen -- Biochemical analysis of the native trail death-inducing signaling complex / Henning Walczak and Tobias L. Haas -- Laser microdissection sample preparation for RNA analyses / Christopher J. Vega.
520 _aOur understanding of the apoptotic pathway and its regulation has improved significantly in the last 10 years. However, as our knowledge of the intricate intracellular events increase, we realize the complexity of the regulatory mechanisms that control it. As such the text describes the performance of contemporary techniques for studying the biology of apoptosis and its role in cancer. This book is a collaboration
650 0 _aCarcinogenesis.
650 0 _aApoptosis.
650 0 _aCancer cells.
650 0 _aCancer
_xGrowth
_xRegulation.
650 1 2 _aNeoplasms
_xphysiopathology
_vLaboratory Manuals.
650 1 2 _aApoptosis
_xphysiology
_vLaboratory Manuals.
650 2 2 _aCaspases
_vLaboratory Manuals.
700 1 _aMor, Gil.
_eeditor.
700 1 _aAlvero, Ayesha B.
_eeditor.
830 0 _aMethods in molecular biology (Clifton, N.J.) ;
_vv. 414.
856 4 1 _3Table of contents
_uhttp://www.loc.gov/catdir/toc/fy0802/2007935895.html
906 _a7
_bcbc
_ccopycat
_d2
_encip
_f20
_gy-gencatlg
942 _2ddc
_cBK