000			03965cam a22004578i 4500
999			_c9872 _d9872
001			17862330
003			OSt
005			20190506093826.0
008			130821s2015 pau b 001 0 eng
010			_a 2013034109
020			_a9781455740666 (hardcover : alk. paper)
035			_a(DNLM)101615568
040			_aDNLM/DLC _cDLC _erda _dDLC
042			_apcc
050	0	0	_aRC268.5 _b.M632 2015
060	1	0	_aQZ 202
082	0	0	_a616.994071 _223 _bM.
245	0	4	_aThe molecular basis of cancer / _cJohn Mendelsohn, MD, Director, Khalifa Institute for Personalized Cancer Therapy and Past President, The University of Texas M.D. Anderson Cancer Center, Houston, Texas; Joe W. Gray, PhD, Gordon Moore Endowed Chair, Chairman, Department of Biomedical Engineering, Director, OHSU Center for Spatial Systems Biomedicine, Associate Director for Translational Research, Knight Cancer Institute, Oregon Health and Science University (OHSU), Portland, Oregon; Peter M. Howley, MD, Shattuck Professor of Pathological Anatomy, Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School, Boston, Massachesetts; Mark A. Israel, MD, Director, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, Professor of Pediatrics and Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; Craig B. Thompson, MD, President and CEO, Memorial Sloan-Kettering Cancer Center, New York, New York.
250			_aEdition 4
264		1	_aPhiladelphia, PA : _bSaunders/Elsevier, _c[2015]
300			_axxiii, 863 pages : _billustrations (some color) ; _c29 cm
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0		_aCancer: A Genetic Disorder -- Oncogenes and Signal Transduction -- Tumor Suppressor Genes -- DNA Repair Pathways and Human Cancer -- Epigenetics and Cancer -- Infectious Agents and Cancer -- Environmental Carcinogenesis -- Animal Models: Flies, Fish, and Yeast -- Genetic Mouse Models of Cancer -- Cancer Stem Cells and the Microenvironment -- Regulation of the Cell Cycle -- Cell Growth -- The Metabolism of Cell Growth and Proliferation -- Apoptosis, Necrosis, and Autophagy -- Cellular Senescence -- The Role of the Microenvironment in Tumor Initiation, Progression, and Metastasis -- Tumor Angiogenesis -- Invasion and Metastasis -- Inflammation and Cancer -- Cancer Systems Biology: The Future -- Biomarkers for Assessing Risk of Cancer -- Protein Biomarkers for Detecting Cancer: Molecular Screening -- The Technology of Analyzing Nucleic Acids in Cancer -- Understanding and Usin
520			_aThe Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice.
650	1	2	_aNeoplasms _xgenetics.
650	1	2	_aNeoplasms _xpathology.
650	2	2	_aMolecular Biology _xmethods.
650	2	2	_aMolecular Targeted Therapy.
700	1		_aMendelsohn, John, _d1936- _eeditor of compilation.
700	1		_aHowley, Peter M., _eeditor of compilation.
700	1		_aIsrael, Mark A., _eeditor of compilation.
700	1		_aGray, Joe W., _eeditor of compilation.
700	1		_aThompson, Craig _q(Craig B.), _eeditor of compilation.
856			_3Abstract _uhttp://repository.fue.edu.eg/xmlui/handle/123456789/1772
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cBK