Ion channel drug discovery /
Ion channel drug discovery /
edited by Brian Cox, Martin Gosling, Horsham Research Centre, Horsham, UK.
- Cambridge : Royal Society of Chemistry, c2015.
- xviii, 366 p. : ill. ; 25 cm.
- RSC drug discovery series, no. 39 2041-3203 ; .
- RSC drug discovery series ; 39. .
"The Queen's Awards for Enterprise: International Trade 2013." pharmacy bookfair2016
Includes bibliographical references and index.
Ion channel drug discovery: a historical perspective / Brian Cox --
High-throughput screening / Alexander Böcker, Sabine Schaertl and Stephen D. Hess --
Automated electrophysiology in ion channel drug discovery / John Dunlop --
Structural understanding of ion channels in atomic detail / Phillip J. Stansfeld --
Voltage-gated sodium channels: structure, function, and molecular pharmacology / William A. Catterall --
AMPA receptor positive allosteric modulators: a case history / Simon E Ward --
The discovery of novel inhaled ENaC blockers for the treatment of cystic fibrosis lung disease / Catherine Howsham and Henry Danahay --
The therapeutic potential of small-molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel / Jia Liu, Gerta Cami-Kobeci, Yiting Wang, Pissared Khuituan, Zhiwei Cai, Hongyu Li, Stephen M. Husbands and David N. Sheppard --
TRPV1 antagonism: from research to clinic / Mark S. Nash, J. Martin Verkuyl and Gurdip Bhalay --
Open access to the KCNQ channel: retigabine and second generation M-current openers / Johannes Krupp, Anthony M. Rush, Britt-Marie Swahn and Martin Main --
The therapeutic potential of hERG1 K+ channels for treating cancer and cardiac arrhythmias / John Mitcheson and Annarosa Arcangeli --
Does nature do ion channel drug discovery better than us? / Richard J. Lewis, Irina Vetter, Fernanda C. Cardoso, Marco Inserra and Glenn King --
Antibodies as ion channel modulators / Wilson Edwards and Alan D. Wickenden --
Ion channel drug discovery: future perspectives / Martin Gosling.
A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.
9781849731867 (hb) 1849731861
2014434400
GBB282750 bnb
101649799 DNLM
Pharmaceutical chemistry.
Drug development.
Ion channels.
Drug Discovery.
Ion Channels--chemistry.
Drug development.
Ion channels.
Pharmaceutical chemistry.
Chimie pharmaceutique.
Médicaments--Mise au point.
Canaux ioniques.
RM301.25 / .I59 2015
615.19 / I
2015 A-381 QV 745
"The Queen's Awards for Enterprise: International Trade 2013." pharmacy bookfair2016
Includes bibliographical references and index.
Ion channel drug discovery: a historical perspective / Brian Cox --
High-throughput screening / Alexander Böcker, Sabine Schaertl and Stephen D. Hess --
Automated electrophysiology in ion channel drug discovery / John Dunlop --
Structural understanding of ion channels in atomic detail / Phillip J. Stansfeld --
Voltage-gated sodium channels: structure, function, and molecular pharmacology / William A. Catterall --
AMPA receptor positive allosteric modulators: a case history / Simon E Ward --
The discovery of novel inhaled ENaC blockers for the treatment of cystic fibrosis lung disease / Catherine Howsham and Henry Danahay --
The therapeutic potential of small-molecule modulators of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel / Jia Liu, Gerta Cami-Kobeci, Yiting Wang, Pissared Khuituan, Zhiwei Cai, Hongyu Li, Stephen M. Husbands and David N. Sheppard --
TRPV1 antagonism: from research to clinic / Mark S. Nash, J. Martin Verkuyl and Gurdip Bhalay --
Open access to the KCNQ channel: retigabine and second generation M-current openers / Johannes Krupp, Anthony M. Rush, Britt-Marie Swahn and Martin Main --
The therapeutic potential of hERG1 K+ channels for treating cancer and cardiac arrhythmias / John Mitcheson and Annarosa Arcangeli --
Does nature do ion channel drug discovery better than us? / Richard J. Lewis, Irina Vetter, Fernanda C. Cardoso, Marco Inserra and Glenn King --
Antibodies as ion channel modulators / Wilson Edwards and Alan D. Wickenden --
Ion channel drug discovery: future perspectives / Martin Gosling.
A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.
9781849731867 (hb) 1849731861
2014434400
GBB282750 bnb
101649799 DNLM
Pharmaceutical chemistry.
Drug development.
Ion channels.
Drug Discovery.
Ion Channels--chemistry.
Drug development.
Ion channels.
Pharmaceutical chemistry.
Chimie pharmaceutique.
Médicaments--Mise au point.
Canaux ioniques.
RM301.25 / .I59 2015
615.19 / I
2015 A-381 QV 745