Unifying microbial mechanisms : shared strategies of pathogenesis /
Cole, Michael F.
Unifying microbial mechanisms : shared strategies of pathogenesis / Michael F. Cole - xviii, 345 pages : color illustrations ; 26 cm.
Introduction to pathogenesis --
Normal microbiotas of the human body --
Biofilms --
Adhesion to host surfaces --
Facilitated cell entry --
Exotoxins and endotoxins --
Extracellular degradative enzymes --
Evasion of the human innate immune system --
Evasion of the human adaptive immune system --
Persistent and latent infections.
Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject
Mike Cole is an experienced instructor at Georgetown University where he is professor of microbiology and immunology and teaches microbial pathogenesis, immunology, and bacteriology. His research interests are into the regulation of commensal and pathogenic bacteria at the mucosal surface by the secretory immune response and the ontogeny of the secretory immune system. He regularly attends the ASM education conference and is the author of half the bacterial cases in Case Studies in Infectious Disease
9780815345404 0815345402 9780429557835 0429557833 9780429553363 0429553366 9780429562303 0429562306
9780429262777 Taylor & Francis
Infection--Microbiology
Immunity.
Host-parasite relationships.
RB152
616.071 / C.M.U
Unifying microbial mechanisms : shared strategies of pathogenesis / Michael F. Cole - xviii, 345 pages : color illustrations ; 26 cm.
Introduction to pathogenesis --
Normal microbiotas of the human body --
Biofilms --
Adhesion to host surfaces --
Facilitated cell entry --
Exotoxins and endotoxins --
Extracellular degradative enzymes --
Evasion of the human innate immune system --
Evasion of the human adaptive immune system --
Persistent and latent infections.
Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject
Mike Cole is an experienced instructor at Georgetown University where he is professor of microbiology and immunology and teaches microbial pathogenesis, immunology, and bacteriology. His research interests are into the regulation of commensal and pathogenic bacteria at the mucosal surface by the secretory immune response and the ontogeny of the secretory immune system. He regularly attends the ASM education conference and is the author of half the bacterial cases in Case Studies in Infectious Disease
9780815345404 0815345402 9780429557835 0429557833 9780429553363 0429553366 9780429562303 0429562306
9780429262777 Taylor & Francis
Infection--Microbiology
Immunity.
Host-parasite relationships.
RB152
616.071 / C.M.U