Unifying microbial mechanisms : shared strategies of pathogenesis / Michael F. Cole

By:

Cole, Michael F [author]

Material type: Text

TextPublisher: Boca Raton : CRC Press, 2020Description: xviii, 345 pages : color illustrations ; 26 cmContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9780815345404
0815345402
9780429557835
0429557833
9780429553363
0429553366
9780429562303
0429562306

Subject(s):

Additional physical formats: Print version:: Unifying microbial mechanisms.DDC classification:

616.071 23 C.M.U

LOC classification:

RB152

Contents:

Summary: Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject

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Holdings
Item type	Current library	Collection	Call number	Copy number	Status	Date due	Barcode
Books	Main library A11	Pharmacy ( Microbiology )	616.071 C.M.U (Browse shelf(Opens below))	1	Available		00015023

Introduction to pathogenesis --
Normal microbiotas of the human body --
Biofilms --
Adhesion to host surfaces --
Facilitated cell entry --
Exotoxins and endotoxins --
Extracellular degradative enzymes --
Evasion of the human innate immune system --
Evasion of the human adaptive immune system --
Persistent and latent infections.

Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject

Mike Cole is an experienced instructor at Georgetown University where he is professor of microbiology and immunology and teaches microbial pathogenesis, immunology, and bacteriology. His research interests are into the regulation of commensal and pathogenic bacteria at the mucosal surface by the secretory immune response and the ontogeny of the secretory immune system. He regularly attends the ASM education conference and is the author of half the bacterial cases in Case Studies in Infectious Disease