Handbook of basic pharmacokinetics-- including clinical applications /
Ritschel, W. A.
Handbook of basic pharmacokinetics-- including clinical applications / Wolfgang A. Ritschel, Gregory L. Kearns - fifth edition - xiv, 563 pages. : illustrations. ; 22 cm
Includes bibliographical references and index
1. Definitions and glossary --
2. LADMER system --
liberation, absorption, distribution, metabolism, elimination, and response --
3. Organs, tissues, cells, and organelles --
4. Cell membranes --
5. Drug-receptor interactions --
6. Absorption/transport mechanisms --
7. pK[subscript a] and degree of ionization --
8. Lipid/water partition coefficient --
9. Physicochemical factors altering biological performance of drugs --
10. Biopharmaceutical data of the gastrointestinal tract --
11. Fluid compartments and circulatory system --
12. Binding of drugs to biological material --
13. Drug biotransformation --
14. Compartment models --
15. Determination of rate constants --
16. Volume of distribution and distribution coefficient --
17. Excretion and clearance of drugs --
18. Urinary and biliary recycling --
19. Cumulative urinary excretion --
20. Area under the blood level-time curve --
21. Pharmacokinetics of single dose administration --
22. Pharmacokinetics of multiple dosing --
23. Compartment model independent analysis --
24. Pediatric pharmacokinetics --
25. Drug dosage in elderly patients --
26. Drug dosage in obese patients --
27. Drug disposition in pregnancy --
28. Dosage regimen design --
29. Drug monitoring and dose adjustment --
30. Physiological and pathological factors influencing drug response --
31. First dose size in man --
32. Forensic pharmacokinetics --
33. Nonlinear pharmacokinetics --
34. Curve fitting --
35. Correlation of clinical response with drug disposition --
36. Bioavailability and bioequivalence --
37. Body surface areas --
38. Extracorporeal methods of drug removal --
39. Pharmacogenetics and pharmacogenomics.
0917330730 (pbk.)
98043913
Pharmacokinetics--Handbooks, manuals, etc
Pharmacokinetics
Handbooks
RM301.5 / .R57 1999
615.7 / R.W.H
QV 38 / R612h 1999
Handbook of basic pharmacokinetics-- including clinical applications / Wolfgang A. Ritschel, Gregory L. Kearns - fifth edition - xiv, 563 pages. : illustrations. ; 22 cm
Includes bibliographical references and index
1. Definitions and glossary --
2. LADMER system --
liberation, absorption, distribution, metabolism, elimination, and response --
3. Organs, tissues, cells, and organelles --
4. Cell membranes --
5. Drug-receptor interactions --
6. Absorption/transport mechanisms --
7. pK[subscript a] and degree of ionization --
8. Lipid/water partition coefficient --
9. Physicochemical factors altering biological performance of drugs --
10. Biopharmaceutical data of the gastrointestinal tract --
11. Fluid compartments and circulatory system --
12. Binding of drugs to biological material --
13. Drug biotransformation --
14. Compartment models --
15. Determination of rate constants --
16. Volume of distribution and distribution coefficient --
17. Excretion and clearance of drugs --
18. Urinary and biliary recycling --
19. Cumulative urinary excretion --
20. Area under the blood level-time curve --
21. Pharmacokinetics of single dose administration --
22. Pharmacokinetics of multiple dosing --
23. Compartment model independent analysis --
24. Pediatric pharmacokinetics --
25. Drug dosage in elderly patients --
26. Drug dosage in obese patients --
27. Drug disposition in pregnancy --
28. Dosage regimen design --
29. Drug monitoring and dose adjustment --
30. Physiological and pathological factors influencing drug response --
31. First dose size in man --
32. Forensic pharmacokinetics --
33. Nonlinear pharmacokinetics --
34. Curve fitting --
35. Correlation of clinical response with drug disposition --
36. Bioavailability and bioequivalence --
37. Body surface areas --
38. Extracorporeal methods of drug removal --
39. Pharmacogenetics and pharmacogenomics.
0917330730 (pbk.)
98043913
Pharmacokinetics--Handbooks, manuals, etc
Pharmacokinetics
Handbooks
RM301.5 / .R57 1999
615.7 / R.W.H
QV 38 / R612h 1999