Handbook of basic pharmacokinetics-- including clinical applications / Wolfgang A. Ritschel, Gregory L. Kearns

By:

Ritschel, W. A. (Wolfgang A.) [Author.]

Contributor(s):

Kearns, Gregory L [Author.]

Material type: Text

TextPublisher: Washington, D.C. : American Pharmaceutical Association, c1999Copyright date: c1999Edition: fifth editionDescription: xiv, 563 pages. : illustrations. ; 22 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

ISBN:

0917330730 (pbk.)

Subject(s):

Genre/Form:

Handbooks

DDC classification:

615.7 21 R.W.H

LOC classification:

RM301.5 .R57 1999

NLM classification:

QV 38

Contents:

1. Definitions and glossary -- 2. LADMER system -- liberation, absorption, distribution, metabolism, elimination, and response -- 3. Organs, tissues, cells, and organelles -- 4. Cell membranes -- 5. Drug-receptor interactions -- 6. Absorption/transport mechanisms -- 7. pK[subscript a] and degree of ionization -- 8. Lipid/water partition coefficient -- 9. Physicochemical factors altering biological performance of drugs -- 10. Biopharmaceutical data of the gastrointestinal tract -- 11. Fluid compartments and circulatory system -- 12. Binding of drugs to biological material -- 13. Drug biotransformation -- 14. Compartment models -- 15. Determination of rate constants -- 16. Volume of distribution and distribution coefficient -- 17. Excretion and clearance of drugs -- 18. Urinary and biliary recycling -- 19. Cumulative urinary excretion -- 20. Area under the blood level-time curve -- 21. Pharmacokinetics of single dose administration -- 22. Pharmacokinetics of multiple dosing -- 23. Compartment model independent analysis -- 24. Pediatric pharmacokinetics -- 25. Drug dosage in elderly patients -- 26. Drug dosage in obese patients -- 27. Drug disposition in pregnancy -- 28. Dosage regimen design -- 29. Drug monitoring and dose adjustment -- 30. Physiological and pathological factors influencing drug response -- 31. First dose size in man -- 32. Forensic pharmacokinetics -- 33. Nonlinear pharmacokinetics -- 34. Curve fitting -- 35. Correlation of clinical response with drug disposition -- 36. Bioavailability and bioequivalence -- 37. Body surface areas -- 38. Extracorporeal methods of drug removal -- 39. Pharmacogenetics and pharmacogenomics.

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Books	Main library A11	Pharmacy ( Pharmaceutical Technology )	615.7 R.W.H (Browse shelf(Opens below))	Available		00016127

Includes bibliographical references and index

1. Definitions and glossary --
2. LADMER system --
liberation, absorption, distribution, metabolism, elimination, and response --
3. Organs, tissues, cells, and organelles --
4. Cell membranes --
5. Drug-receptor interactions --
6. Absorption/transport mechanisms --
7. pK[subscript a] and degree of ionization --
8. Lipid/water partition coefficient --
9. Physicochemical factors altering biological performance of drugs --
10. Biopharmaceutical data of the gastrointestinal tract --
11. Fluid compartments and circulatory system --
12. Binding of drugs to biological material --
13. Drug biotransformation --
14. Compartment models --
15. Determination of rate constants --
16. Volume of distribution and distribution coefficient --
17. Excretion and clearance of drugs --
18. Urinary and biliary recycling --
19. Cumulative urinary excretion --
20. Area under the blood level-time curve --
21. Pharmacokinetics of single dose administration --
22. Pharmacokinetics of multiple dosing --
23. Compartment model independent analysis --
24. Pediatric pharmacokinetics --
25. Drug dosage in elderly patients --
26. Drug dosage in obese patients --
27. Drug disposition in pregnancy --
28. Dosage regimen design --
29. Drug monitoring and dose adjustment --
30. Physiological and pathological factors influencing drug response --
31. First dose size in man --
32. Forensic pharmacokinetics --
33. Nonlinear pharmacokinetics --
34. Curve fitting --
35. Correlation of clinical response with drug disposition --
36. Bioavailability and bioequivalence --
37. Body surface areas --
38. Extracorporeal methods of drug removal --
39. Pharmacogenetics and pharmacogenomics.

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