MARC details
| 000 -LEADER |
| fixed length control field |
05562cam a2200421 i 4500 |
| 001 - CONTROL NUMBER |
| control field |
18456119 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
| control field |
20160228123615.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
150120s2014 ne a b 001 0 eng c |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
| LC control number |
2014497397 |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
| Record control number |
101636996 |
| Source |
DNLM |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
| International Standard Book Number |
9780124104716 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
| International Standard Book Number |
0124104711 |
| 035 ## - SYSTEM CONTROL NUMBER |
| System control number |
(OCoLC)ocn891353974 |
| 040 ## - CATALOGING SOURCE |
| Original cataloging agency |
NLM |
| Language of cataloging |
eng |
| Transcribing agency |
NLM |
| Description conventions |
rda |
| Modifying agency |
DLC |
| 042 ## - AUTHENTICATION CODE |
| Authentication code |
pcc |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
| Classification number |
QH324.2 |
| Item number |
.C438 2014 |
| 060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
| Classification number |
2014 H-918 |
| 060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
| Classification number |
QU 26.5 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
| Edition number |
22 |
| Classification number |
570.285 |
| Item number |
C.S.B |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
| Personal name |
Choudhuri, Supratim, |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
| Title |
Bioinformatics for beginners : |
| Remainder of title |
genes, genomes, molecular evolution, databases and analytical tools / |
| Statement of responsibility, etc |
Supratim Choudhuri, with contribution from Dr. Michael Kotewicz on the optical mapping of DNA, Center for food Safety and Applied Nutrition, FDA, College Park, Maryland. |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
| Place of publication, distribution, etc |
Amsterdam ; |
| -- |
Boston : |
| Name of publisher, distributor, etc |
Elsevier/AP, Academic Press is an imprint of Elsevier, |
| Date of publication, distribution, etc |
2014. |
| 300 ## - PHYSICAL DESCRIPTION |
| Extent |
xi, 225 pages : |
| Other physical details |
illustrations (some color) ; |
| Dimensions |
29 cm |
| 336 ## - CONTENT TYPE |
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
| Media type term |
unmediated |
| Media type code |
n |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
| Carrier type term |
volume |
| Carrier type code |
nc |
| Source |
rdacarrier |
| 500 ## - GENERAL NOTE |
| General note |
pharmacy bookfair2016 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
| Formatted contents note |
Front Cover; Bioinformatics for beginners; Copyright Page;<br/> Contents; Preface; Acknowledgment; 1 Fundamentals of Genes<br/> and Genomes; 1.1 Biological Macromolecules, Genomics, and <br/> Bioinformatics; 1.2 DNA as the Universal Genetic Material;<br/> 1.3 DNA Double Helix; 1.3.1 Structural Units of DNA; 1.3.2<br/> Linkage between Nucleotides; 1.3.3 Base-Pairing Rules, <br/> Double Helix, and Triple Helix; 1.3.4 Single-Stranded DNA;<br/> 1.3.5 Base Sequence and the Genetic Code; 1.4 <br/> Conformations of DNA; 1.5 Typical Eukaryotic Gene <br/> Structure; 1.5.1 Transcribed Region; 1.5.1.1 Intron-<br/> Splicing Signals. <br/>1.5.1.2 Effect of Intron Phase on Alternative <br/> Splicing1.5.1.3 Evolution of Introns; 1.5.2 52 Flanking <br/> Region of Transcribed Genes; 1.5.3 32 Flanking Region of <br/> Transcribed Genes; 1.6 Mutations in the DNA Sequence; 1.7 <br/> Some Features of RNA; 1.7.1 Instability of mRNA; 1.7.2 52 <br/> and 32 Untranslated Regions of mRNA; 1.7.3 Secondary <br/> Structures in RNA; 1.8 Coding Versus Noncoding RNA; 1.8.1 <br/> Small Noncoding RNA, Long Noncoding RNA, Competing <br/> Endogenous RNA, and Circular RNA; 1.9 Protein Structure <br/> and Function; 1.9.1 Configuration and Chirality of Amino <br/> Acids; 1.9.2 Ionic Character of Amino Acids. <br/>1.9.3 Relationship between Protein Function and the <br/> Location of Amino Acids in the Polypeptide Chain1.9.4 <br/> Linkage between Amino Acids-The Peptide Bond; 1.9.5 Four <br/> Levels of Protein Structure; 1.9.6 Acidic and Basic <br/> Proteins; 1.9.7 Nonstandard Amino Acids in Polypeptide <br/> Chains; 1.10 Genome Structure and Organization; 1.10.1 The<br/> Structure of a Representative Genome-The Human Genome; <br/> 1.10.2 Functional Sequence Elements in the Genome; <br/> 1.10.2.1 Promoters; 1.10.2.2 Enhancers; 1.10.2.3 Locus <br/> Control Regions; 1.10.2.4 Insulators. <br/>1.10.3 Epigenetic Modifications of the Genome Can Edit the<br/> Language Written in the DNA Sequence and Add an Extra <br/> Layer of C ... 1.10.3.1 Histone Code; 1.10.3.2 The <br/> Dynamics of Epigenetic Changes; 1.10.4 Lessons Learned <br/> from the Second Phase of the ENCODE Project about the DNA <br/> Elements in the Human Genome and its Epige ... ; <br/> References; 2 Fundamentals of Molecular Evolution; 2.1 <br/> Bioinformatics, Molecular Evolution, and Phylogenetics; <br/> 2.2 Biological Evolution and Basic Premises of Darwinism; <br/> 2.2.1 First Experimental Demonstration of Evolutionary <br/> Principles in the Test Tube. <br/>2.3 Molecular Basis of Heritable Genetic Variations-The <br/> Raw Materials for Evolution2.3.1 Molecular Basis of <br/> Mutation; 2.3.2 Recombination and Generation of Genetic <br/> Diversity; 2.3.3 Gene Flow and Introduction of Genetic <br/> Diversity; 2.3.4 Origin of New Genes, Creation of Genetic <br/> Diversity and Genome Evolution; 2.3.4.1 Origin of New <br/> Genes from Coding Sequences (Pre-existing Genes); <br/> 2.3.4.1.a Gene Duplication and the 2R Hypothesis; <br/> 2.3.4.1.b Exon Shuffling; 2.3.4.1.c Gene Fusion and <br/> Fission; 2.3.4.1.d Horizontal Gene Transfer; 2.3.4.2 <br/> Origin (de Novo) of New Genes from Noncoding Sequences. |
| 520 ## - SUMMARY, ETC. |
| Summary, etc |
Bioinformatics for Beginners provides a coherent and <br/> friendly treatment of bioinformatics for any student or <br/> scientist within biology who has not routinely performed <br/> bioinformatic analysis. The book discusses relevant <br/> principles needed to understand the theoretical <br/> underpinnings of bioinformatic analysis, and demonstrates <br/> with examples targeted analysis using freely available web<br/> -based software and publicly available databases. <br/> Eschewing non-essential information, the work focuses on <br/> principles and hands-on analysis and points to many <br/> further study options. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Computational biology. |
| 9 (RLIN) |
8467 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Computational biology |
| General subdivision |
Methods. |
| 9 (RLIN) |
8467 |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Computational Biology. |
| 9 (RLIN) |
8467 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| Personal name |
Kotewicz, Michael, |
| Relator term |
author. |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
| a |
7 |
| b |
cbc |
| c |
pccadap |
| d |
2 |
| e |
ncip |
| f |
20 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Books |