MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03759ntm a2200325 i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
12102116 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20211025112156.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150118s2020 ua a f bm 000 0 eng | |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-EULC |
| Transcribing agency |
EG-EULC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract/overprinted title or subtitle |
ara |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Item number |
I.E.P |
| Edition number |
22 |
| Classification number |
615.19 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ibrahim, Enas El-Maghawry, |
| 9 (RLIN) |
33874 |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
A pharmaceutical study on colon-targeted delivery systems of an anti-inflammatory drug / |
| Statement of responsibility, etc |
Enas El-Maghawry Ibrahim, (assistant lecturer, department of Pharmaceutics & Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt), supervision of Prof. Dr. Ahmed Abd-Elbary (Professor of Pharmaceutics and Industrial Pharmacy, Ex-Dean of Faculty of Pharmacy, Cairo University, Beni SweifUniversity), Prof. Dr. Seham Elkheshen, (Professor of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University), Prof. Dr. Mina Ibrahim Tadros, (Professor of Pharmaceutics and Industrial Pharmacy, Dean of Faculty of Pharmacy and Drug Technology, Egyptian Chinese University). |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
دراسة صيدلية على بعض الأنظمة الهادفة للقولون المحتوية على عقار مضاد للالتهاب |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Date of publication, distribution, etc |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
x, 212 pages, 6 pages : |
| Other physical details |
illustrations (some color) ; |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
|---|
| General note |
supervision of Prof. Dr. Ahmed Abd-Elbary (Professor of Pharmaceutics and Industrial Pharmacy, Ex-Dean of Faculty of Pharmacy, Cairo University, Beni Sweif University), Prof. Dr. Seham Elkheshen, (Professor of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University), Prof. Dr. Mina Ibrahim Tadros, (Professor of Pharmaceutics and Industrial Pharmacy, Dean of Faculty of Pharmacy and Drug Technology, Egyptian Chinese University). |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.)- Cairo university, Faculty of pharmacy, Department of Pharmaceutics and industrial Pharmacy, 2020. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references. |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc |
Colon-targeted drug delivery has been the focus of numerous studies due to its potential to improve treatment of local diseases affecting the colon, while minimizing systemic drug side effects. Some examples of the diseases which impact the colon include Crohn’s disease (CD) and ulcerative colitis (UC). <br/>In literature, different strategies have been used to target the inflamed colon after oral drug administration. Strategies for specific colon drug delivery include the utilization of pro-drugs, exploitation of higher colonic pH values, and enzymatic activity of colonic micro flora, intestinal transit time and colonic pressure.<br/>In general, dimensions of the delivery system greatly influence the targeting of the inflamed colon. Size-dependency of particles has a considerable impact on their epithelial uptake. A favoured accumulation in the inflamed colon tissues has been found for particles having sizes in the nanometer-range. It has been shown in experimental colitis models that nanosized particles are more readily uptaken by cells that are immune-related such as macrophages or dendritic cells in the site of active inflammation. <br/>The nano spray drying is one of the advanced technologies to produce nanoparticles. The nano spray dryer can produce relatively high yield of nanosized particles which possess narrow particle size distributions. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English, abstracts in English and Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmaceutical industry |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacology |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
DSpace electronic resource |
| Uniform Resource Identifier |
<a href="http://repository.fue.edu.eg/xmlui/handle/123456789/5777">http://repository.fue.edu.eg/xmlui/handle/123456789/5777</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Thesis |
| Source of classification or shelving scheme |
Dewey Decimal Classification |